Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia

Abstract

In this research, silver-seeded PVC was synthesised and modified to combat ventilator-associated pneumonia by preventing bacterial adherence. The silver-seeded PVC was synthesised by in situ deposition of silver particles, and the silver-seeded PVC was further modified by reacting with 3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-heptadecafluoro-1-decanethiol to create a superhydrophobic surface with static water contact angle more than 150°. The silver-coated PVC and superhydrophobic silver-coated PVC both exhibited excellent anti-adherent activity against MRSA and Pseudomonas aeruginosa.

Keywords

PVC, Superhydrophobic, anti-adherence, VAP

How to Cite

Li, J., Wylie, M. & McCoy, C. P., (2022) “Synthesis and modification of silver-seeded PVC for use as anti-adherent materials to prevent ventilator-associated pneumonia”, British Journal of Pharmacy 7(2). doi: https://doi.org/10.5920/bjpharm.1126

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Authors

Jia Li (Queen's University Belfast)
Matthew Wylie (Queen's University Belfast)
Colin P McCoy (Queen's University Belfast)

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Creative Commons Attribution 4.0

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This article has been peer reviewed.

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