Effect of Process Parameters on the critical attributes of the Liposomal formulations

Abstract

This study investigate the effect of process parameters on the size, distribution, zeta potential  and loading efficiency for the co-delivery of liposomal formulation of Ran-RCC1 inhibitory peptide (RANIP) and doxorubicin (DOX) to breast cancer. The results show that drug concentration, pH and ultrasound intensity are all critical factors to control the attributes of the liposomes.


Keywords

Liposomes, Drug-delivery, Formulations, stability

How to Cite

Abu Ras, B., Haggag, Y., Isreb, M. & El Tanani, M., (2022) “Effect of Process Parameters on the critical attributes of the Liposomal formulations”, British Journal of Pharmacy 7(2). doi: https://doi.org/10.5920/bjpharm.1172

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Authors

Bayan Abu Ras (ICT)
Youssef Haggag (Faculty of Pharmacy)
Mohammad Isreb (University of Bradford)
Mohamed El Tanani (ICT)

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Creative Commons Attribution 4.0

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This article has been peer reviewed.

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