Impact of molecular weight of polyethylene glycol on physicochemical characteristics of polymeric nanoparticles encapsulating pimozide.

Abstract

.  However, PEG molecular weight has a significant effect on key parameters of nanoparticles such as Size and encapsulation efficiency. In this study, PLGA-PEG nanoparticles with Pimozide were prepared using a microfluidic technique using two different molecular weights of PEG. Physicochemical characterizations were undertaken including Encapsulation efficiency and Fourier transform infrared spectroscopy (FTIR). Results were compared for these two formulations to understand how the weight variation of PEG impacts on physicochemical properties of nanoparticles.    

 

Keywords

PLGA, PEGlyation, PLGA-PEG, nanoparticles

How to Cite

Barad, H., Elkordy, A. A. & Faheem, A. M., (2023) “Impact of molecular weight of polyethylene glycol on physicochemical characteristics of polymeric nanoparticles encapsulating pimozide.”, British Journal of Pharmacy 8(2). doi: https://doi.org/10.5920/bjpharm.1409

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Authors

HardipSinh Barad (University of Sunderland)
Amal Ali Elkordy (University of Sunderland)
Ahmed M Faheem orcid logo (university of sunderland)

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Creative Commons Attribution 4.0

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This article has been peer reviewed.

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