Understanding the Integrity of Coating for Taste-Masked Granules – Before and After Tablet Compression

Abstract

Raman microscopy was used to visualize the integrity of a barrier membrane coating at the various stage of chewable tablets development. The effect of substrate morphology and particle characteristics was found to be important in maintaining the integrity of the coating throughout the process of chewable tablets manufacture. Furthermore, the observations from the Raman image analysis provide an understanding of the factors affecting drug release.

Keywords

taste masking, raman microscopy, granules, tablets

How to Cite

Ghimire M. (2018) “Understanding the Integrity of Coating for Taste-Masked Granules – Before and After Tablet Compression”, British Journal of Pharmacy. 2(2). doi: https://doi.org/10.5920/bjpharm.2017.17

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Authors

Manish Ghimire

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Creative Commons Attribution 4.0

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This article has been peer reviewed.

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