The Use Of XRPD And ATR-FTIR In The Screening Of Three Component Co-amorphous Systems Created Via A Melt-Quench Method.

Abstract

Multiple three-component co-amorphous systems have been created via a melt- quench method. This has been confirmed by a single glass transition in the individual DSC traces and then reinforced by X-ray diffraction data, which show an absence of crystalline material. ATR-FTIR has also been used to show a change in bonding vibrations between the physical mixtures and co-amorphous samples. The change in bonding vibrations indicates different molecular interactions within the co-amorphous materials.

Keywords

ATR-FTIR, XRD, TGA, DSC, co-amorphous

How to Cite

Edgar B. & D'Angelo A. & Antonjievic M. D., (2018) “The Use Of XRPD And ATR-FTIR In The Screening Of Three Component Co-amorphous Systems Created Via A Melt-Quench Method.”, British Journal of Pharmacy 2(2). doi: https://doi.org/10.5920/bjpharm.2017.24

193

Views

77

Downloads

Share

Authors

Benjamin Edgar
Alessandra D'Angelo

Milan D Antonjievic

Download

Issue

Dates

Licence

Creative Commons Attribution 4.0

Identifiers

Peer Review

This article has been peer reviewed.

File Checksums (MD5)

  • : 2abd61c6dc9a4b23263601aa52e89af0