The Use Of XRPD And ATR-FTIR In The Screening Of Three Component Co-amorphous Systems Created Via A Melt-Quench Method.

Abstract

Multiple three-component co-amorphous systems have been created via a melt- quench method. This has been confirmed by a single glass transition in the individual DSC traces and then reinforced by X-ray diffraction data, which show an absence of crystalline material. ATR-FTIR has also been used to show a change in bonding vibrations between the physical mixtures and co-amorphous samples. The change in bonding vibrations indicates different molecular interactions within the co-amorphous materials.

Keywords

ATR-FTIR, XRD, TGA, DSC, co-amorphous

How to Cite

Edgar, B., D'Angelo, A. & Antonjievic, M. D., (2018) “The Use Of XRPD And ATR-FTIR In The Screening Of Three Component Co-amorphous Systems Created Via A Melt-Quench Method.”, British Journal of Pharmacy 2(2). doi: https://doi.org/10.5920/bjpharm.2017.24

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Authors

Benjamin Edgar
Alessandra D'Angelo
Milan D Antonjievic

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Creative Commons Attribution 4.0

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